TCN e-Systems // Ideal Site Selection

Case Studies

	Speeding the Development of Global Recruitment Materials
	Ideal Site Selection
	Optimizing Site and Monitor Performance

Forward to a Colleague

To send this information to a colleague, click here.

Learn More

Ideal Site Selection

Combining product suites and enhancing services was the right approach for ultimately achieving enrollment for a clinical study of a treatment for immune thrombocytopenic purpura. It enabled the sponsor to a.) identify the required attributes of the ideal investigative practice, b.) determine the optimal locations for sites in order to reach sufficient numbers of patients, and c.) identify a wealth of potential sites, from which the sponsor was able to select the best practices.

Study

Phase III
U.S.-based
170 patients

Objectives

Identify and select a sufficient number of new sites to make up a severe enrollment shortfall.

Recruitment Challenges

The low incidence of the condition
High number of ITP studies competing for the same limited patient pool

Toolkit

Product/Enhancement	Essential Use	Learn More
SiteOPTIMIZER	For determining the study's specific enrollment challenges and assessing potential sites.	Learn More >
Market Research	For augmenting SiteOPTIMIZER in establishing the essential criteria that sites must meet.	Learn More >
GeoPopulation Analyzer	For identifying the ideal locations for potential sites, based on populations of patients who met the key eligibility criteria for the study.	Learn More >
StudyFORECASTER	For projecting each potential site's ability to meet enrollment goals.	Learn More >
TrialCENTRALNet	For centralizing all existing and potential site information.	Learn More >

Results

SiteOPTIMIZER and Market Research identified the ideal investigator as a hematologist specializing in ITP whose treatment philosophy aligned with the novel science of the investigational drug, and helped to establish a clear set of essential criteria by which to assess potential sites' individual strengths and weaknesses.
The population mapping algorithms of GeoPopulation Analyzer provided 16 markets in which it would be most feasible to locate new investigative sites.
The information gathered through SiteOPTIMIZER's surveys of potential sites enabled realistic enrollment projections with StudyFORECASTER about whether a potential site could actually recruit the required number of patients within the enrollment period.
All told, this customized e-recruitment toolkit identified more than 90 potential sites that qualified as "superior." What's more, it revealed that only the top 40 would be needed, if sufficiently supported, saving the sponsor time, money, and effort in contracting and initiating sites.

[ back to top ]